Greater than a dozen randomized controlled trials have since proven that ketogenic diets significantly and safely stabilize neuronal networks, quelling seizures in many patients with epilepsy. A rising physique of evidence that includes Sethi’s analysis suggests the weight loss plan, or ketogenic metabolic therapy as she prefers to call it, also can assist patients with serious psychological illness equivalent to depression, schizophrenia and bipolar disorder. The relatively new area of metabolic psychiatry, founded at Stanford Medicine by Sethi, focuses on addressing metabolic dysfunction with ketogenic and other metabolism-targeted therapies to improve mental health outcomes. Keto therapy stabilizes neurons and reduces inflammation in the brain. Ketogenic therapy increases the ratio of gamma-aminobutyric acid to glutamate in neurons. Balancing these inhibitory and excitatory neurotransmitters helps suppress extreme neuronal firing that contributes to sure forms of psychological illness. Bipolar mania includes fluctuations in power states in which neuronal firing is extra unstable,&quot