These tails are subject to several post-translational covalent modifications, including acetylation, phosphorylation, ubiquitination, sumoylation and methylation (reviewed in 1 ). Methylation been found on a range of lysine residues in various histones: lawyer in my area K4 (utilizing the one-letter amino-acid code for lysine), K9, K27, K36 and K79 lawyers in my area histone H3, Legal Practice K20 in histone H4, K59 in the globular area of histone H4 2 and K26 of histone H1B 3 A number of proteins liable for the methylation of specific residues have been characterised, and legal practice all but certainly one of these contains a SET area