Thus, my first week of reverse weight-reduction plan entails elevating my every day consumption by 25 grams of carbohydrate, or a hundred calories. The exception to the rule is the DOT1 household, members of which methylate K79 in the globular region of histone H3 and that are structurally not associated to SET-area proteins 4 - 6 Latest work means that SET-domain-containing proteins methylate just a few proteins along with histones (see later)